FCPS OBG Part 1 – Practice Questions – Physiology

1. A 32-year-old primiparous woman suffers a massive antepartum haemorrhage and undergoes an emergency caesarean section. During the caesarean section she suffers a massive obstetric haemorrhage requiring transfusion of blood and clotting factors. As a result of these events, she develops disseminated intravascular coagulopathy. Which of the following laboratory results would be expected in this condition?

2. A 23-year-old woman develops a fever and has offensive vaginal discharge and abdominal pain. You are concerned that she is septic and wish to administer intravenous antibiotics. Prior to administration you wish to calculate her estimated glomerular filtration rate (eGFR) in order to dose her antibiotic therapy appropriately. Which of the following factors is included when calculating eGFR?

3. A 25-year-old primiparous woman attends antenatal clinic for a routine check at 28 weeks’ gestation. Her urine dipstick shows glucose 2+. On questioning, she has just eaten a doughnut. Which of the following describes the sequential handling of glucose by the kidney?

4. A 37-year-old woman attends her general practitioner for contraceptive advice. She is a smoker of 10 cigarettes a day and has had two children. She is keen to try the progesterone-only pill and asks you how it works. Which is the most appropriate answer?

5. A 72-year-old woman undergoes a total abdominal hysterectomy. She has chronic obstructive pulmonary disease. Postoperatively, she is difficult to extubate and has a prolonged stay on the intensive care unit. Which of the following is the most important direct stimulus to respiration?