Biostatistics SBA

1. 21 day Follow-up of a Trial of Remdesivir for SARI COVID was conducted. 441 women received Remdesivir. Mean age at enrolment was 30 years and the SD was 2.1. Calculate the Confidence interval of age?

2. In a multicenter, randomized, noninferiority trial, they compared two threshold values for treatment of asymptomatic Anemia. Mean ± SEM of threshold value of Hb in g% in lower threshold group was 9 ± 0.1 g%. What is the confidence interval of Hb?

3. A 35-Year-Old Woman with severe Anemia was evaluated for its cause. During frequent visits, Hb g% was measured. Following were the recordings: 5.3, 5.4, 5.5, 5.2, 5.1 g/dl. What was the mean Hb?

4. An experimental study was done in pregnant women by randomly assigning each participant either to drug or to placebo. At the end of a year the change in participants’ blood pressure over the year was measured, and the change was compared for the two groups. This is a randomized experiment rather than an observational study because

5. Which one of the following variables is not categorical?

6. A list of glucose in mg/dl recorded in SMBG by Glucometer is: 73, 68, 83, 79, 90. What is the median for this list?

7. In a study the LDL levels in mg/dl were estimated. They were 150,150,199,201,200. Which among the following statement is true?

8. 100 pregnant women with PIH were sampled during the antenatal period to check the incidence of DIC. Presence or absence of DIC is which type of variable?

9. You wish to investigate the difference in time duration it takes to perform assisted vaginal delivery (AVD) on women with and without preeclampsia. The time duration of AVD not normally distributed. We cannot assume time duration of AVD to be normal. Which test would you use to find the significance of difference in time duration of AVD between two groups?

10. You wish to investigate knowledge about breast cancer, knowledge about breast cancer screening, perceived susceptibility, perceived seriousness, and perceived benefits within the intervention group by comparing the before and after intervention scores. The scores were assumed to be normally distributed. Which test you would use?

11. What is true about p value?

12. When assessing the accuracy of a diagnostic test, the best result can be achieved by:

13. Paracetamol in acute postoperative pain: In 28 randomised trials with 3200 patients, the results were as follows: with paracetamol 975 or 1000 mg – 876/1903 (46%) of patients with moderate or severe pain had the outcome of at least 50% pain relief over 6 hours with placebo – 241/1329 (18%) of patients had the same outcome. What is the NNT?

14. You are critically appraising a diagnostic paper on the use of MRI to diagnose severe endometriosis. The paper assesses predictive values of the test but you wish to determine whether the test usefully changes the probability of disease.

Which answer best describes the likelihood ratios and interpretation of the test

15. You are interested in finding out which type of anaesthetic is more comfortable, from a patient’s perspective, for use during a caesarean section – epidural or spinal. Which type of study would you think is the most appropriate to help you answer your question most effectively?